Selected Paper : Synthesis of Biocompatible Polysaccharide Analogues and Their Application to In Vivo Optical Tumor Imaging

• Koji Miki

• Akinori Kimura

• Tatsuhiro Inoue

抄録

Polysaccharide analogues having 2-deoxypsicofuranose as a repeating unit were successfully synthesized by ring-opening metathesis polymerization of 7-oxanorbornene-2,3-diol and dihydroxylation. The amphiphilic polysaccharide analogues conjugated with poly(ethylene glycol), a near-infrared fluorescence dye and a tumor-targeting cyclic arginine–glycine–aspartic acid peptide showed low cytotoxicity in vitro and high tumor-targeting specificity in vivo.

収録刊行物

• Bulletin of the Chemical Society of Japan

  Bulletin of the Chemical Society of Japan 88 (6), 792-803, 2015-06

  Tokyo : Chemical Society of Japan

キーワード

• General Chemistry

詳細情報

• CRID: 1523106604646431872
• NII論文ID: 130005075674
• NII書誌ID: AA00580132
• ISSN: 00092673
• ISSN: 13480634
• DOI: 10.1246/bcsj.20150038
• NDL書誌ID: 026447915
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I026447915
• Web Site: https://academic.oup.com/bcsj/article-pdf/88/6/792/56277930/bcsj.20150038.pdf
• 本文言語コード: en
• NDL 雑誌分類:
  • ZP1(科学技術--化学・化学工業)
• データソース種別:
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN