Features of REM-related Sleep Disordered Breathing in the Japanese Population
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- Sakao Seiichiro
- Department of Respirology (B2), Graduate School of Medicine, Chiba University, Japan
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- Sakurai Takayuki
- Department of Respirology (B2), Graduate School of Medicine, Chiba University, Japan
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- Yahaba Misuzu
- Department of Respirology (B2), Graduate School of Medicine, Chiba University, Japan
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- Sakurai Yoriko
- Department of Respirology (B2), Graduate School of Medicine, Chiba University, Japan
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- Terada Jiro
- Department of Respirology (B2), Graduate School of Medicine, Chiba University, Japan
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- Tanabe Nobuhiro
- Department of Respirology (B2), Graduate School of Medicine, Chiba University, Japan
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- Tatsumi Koichiro
- Department of Respirology (B2), Graduate School of Medicine, Chiba University, Japan
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抄録
Objective Rapid eye movement (REM)-related sleep disordered breathing (SDB) is an entity in which the cessation or reduction of breathing occurs primarily during the REM period. Most studies have shown that REM-related SDB more frequently affects women, younger people and patients with mild or moderate SDB. The aim of this study was to prospectively investigate the prevalence and features of REM-related SDB in Japanese subjects compared with the findings of previous reports.<br> Methods A total of 468 patients were evaluated in this study. The diagnosis of SDB was established using polysomnographic monitoring. The patient variables included age, gender, body characteristics, comorbidities, etc.<br> Results REM-related SDB was more prevalent in women than non-REM-related SDB (male ratio; 66.3% vs. 79.5%, p=0.03). Moreover, the patients with REM-related SDB had lower body mass indexes (25.9±6.9 vs. 28.5±7.7; p=0.003), arousal indexes (31.8±10.7 vs. 61.0±29.1; p<0.001), apnea hypopnea indexes (15.0±8.0 vs. 54.9±35.9) and glycosylated hemoglobin (HbA1c) levels (5.5±0.9 vs. 5.9±2.6; p=0.02) than the patients with non-REM-related SDB. However, the overall and female gender prevalence of REM-related SDB among the Japanese subjects was lower than that shown in previous reports. The finding that REM-related SDB was not prevalent in younger individuals or severely obese patients was not consistent with the results of previous studies.<br> Conclusion The present findings suggest that REM-related SDB may have different clinical characteristics in the Japanese population than that observed in previous reports.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 54 (12), 1481-1487, 2015
一般社団法人 日本内科学会