Atypical Onset of Eosinophilic Granulomatosis with Polyangitis in a Patient with Long-term Well-controlled Bronchial Asthma

  • Akao Satoshi
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Hagiya Hideharu
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Hasegawa Kou
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Nada Takahiro
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Nakamura Eri
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Kimura Kosuke
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Waseda Koichi
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Hanayama Yoshihisa
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Deguchi Kentaro
    Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences
  • Otsuka Fumio
    Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

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Eosinophillic glanuromatosis with polyangitis (EGPA) usually occurs in patients with a recent history (usually less than 10 years) of uncontrolled bronchial asthma. Here we describe a case of EGPA that occurred in a 68-year-old female who had well-controlled bronchial asthma for 17 years. A leukotriene receptor antagonist that had been prescribed one week before onset might have triggered the disease. Our case shows that there is a wide spectrum of clinical characteristics of EGPA, making diagnosis difficult in a primary care setting.

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