Intravascular Large B-Cell Lymphoma Complicated by Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis that was Successfully Treated with Rituximab-Containing Chemotherapy
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- Tsuda Mariko
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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- Nakashima Yasuhiro
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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- Ikeda Motohiko
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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- Shimada Shingo
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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- Nomura Masatoshi
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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- Matsushima Takamitsu
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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- Takahashi Shunsuke
- Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University
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- Aishima Shinichi
- Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University
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- Oda Yoshinao
- Department of Anatomic Pathology, Graduate School of Medical Sciences, Kyushu University
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- Shiratsuchi Motoaki
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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- Takayanagi Ryoichi
- Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University
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抄録
A 64-year-old woman had suffered from painful livedo reticularis for 2 years and was referred to us due to fever, anasarca and paresthesia of the lower limbs. Serum proteinase-3-anti-neutrophil cytoplasmic antibody (ANCA) was positive. Abnormal lymphocytes were found in the cerebrospinal fluid and bone marrow. Skin biopsy revealed large atypical lymphoid cells with CD20 positivity lodged in the small vessels and neutrophilic infiltration into the arterial vascular wall with fibrinoid degeneration. A diagnosis of intravascular large B-cell lymphoma complicated by ANCA-associated vasculitis was made, and rituximab-containing chemotherapy followed by prednisolone was quite effective for both lymphoma and ANCA-associated vasculitis.
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｈｅｍａｔｏｐａｔｈｏｌｏｇｙ
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Ｊｏｕｒｎａｌ ｏｆ Ｃｌｉｎｉｃａｌ ａｎｄ Ｅｘｐｅｒｉｍｅｎｔａｌ Ｈｅｍａｔｏｐａｔｈｏｌｏｇｙ 55 (1), 39-43, 2015
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