経口BP製剤によると考えられた上顎骨壊死の1例

• 加納 慶太

  宇治武田病院歯科・歯科口腔外科

• 村山 高章

  宇治武田病院歯科・歯科口腔外科

書誌事項

タイトル別名

• A Case of Osteonecrosis of the Maxilla Induced by a Bisphosphonate Internal Use

抄録

Recently, many cases of bisphosphonate-related osteonecrosis of the jaw ( BRONJ ) have been reported. BRONJ is usually caused by invasive dental procedures, such as tooth extraction, advanced periodontal disease and prosthetic trauma.<br>We report a case of spontaneous osteonecrosis of the maxilla induced by internal use of a bisphosphonate that was successfully managed by surgical treatment. A 77-year-old female visited our department with a chief complaint of swelling of the right maxilla. Oral examination revealed mild swelling and pus discharge at the right upper gum, and radiographic examination showed osteonecrosis. She had taken BP pills for 3 years beginning in 2009 because of osteoporosis. We found that the diagnosis was spontaneous BRONJ on reviewing her medical history. After treatment of antibiotics and local irrigation, we removed the sequestrum. Histopathological examination revealed sequestration with attachment of bacteria. She has been followed for 20 months since surgery and continues to do well.

収録刊行物

• 日本口腔診断学会雑誌

  日本口腔診断学会雑誌 28 (2), 129-133, 2015

  日本口腔診断学会

キーワード

• ビスフォスフォネート
• 顎骨壊死
• 自然発生
• 外科的治療

詳細情報

• CRID: 1390282680712892544
• NII論文ID: 130005084445
• DOI: 10.15214/jsodom.28.129
• ISSN: 21882843
• ISSN: 09149694
• Web Site: https://search.jamas.or.jp/link/ui/2015319752
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可