Rhabdomyolysis Caused by <i>Candida parapsilosis</i> in a Patient with Acute Myeloid Leukemia after Bone Marrow Transplantation

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  • Kakiuchi Seiji
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Yakushijin Kimikazu
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Yamamoto Katsuya
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Tomioka Hideo
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Inui Yumiko
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Okamura Atsuo
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Kawamoto Shinichiro
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Minami Yosuke
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan Division of Blood Transfusion, Kobe University Hospital, Japan
  • Murayama Tohru
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Ito Mitsuhiro
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Matsuoka Hiroshi
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan
  • Minami Hironobu
    Division of Medical Oncology/Hematology, Department of Medicine, Kobe University Graduate School of Medicine, Japan

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抄録

Rhabdomyolysis is characterized by a marked elevation of the creatine kinase (CK) levels and myoglobinuria, thus leading to renal dysfunction. Various viruses or bacteria can be etiologic agents, but mycosis has only rarely been reported to be a cause of rhabdomyolysis. In this report, we describe an adolescent male with acute myeloid leukemia who underwent allogeneic bone marrow transplantation and thereafter developed rhabdomyolysis and Candida parapsilosis fungemia almost at the same time. Following treatment for C. parapsilosis, the transaminase and CK levels both satisfactorily decreased. This case illustrates that C. parapsilosis infection may be a causative agent of rhabdomyolysis in immunocompromised patients.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 54 (16), 2057-2060, 2015

    一般社団法人 日本内科学会

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