Single-photon emission computed tomography and transcranial color-coded real-time sonography studies can predict hyperperfusion syndrome after carotid artery stenting

  • Iwata Tomonori
    Department of Stroke Treatment, Shonan Kamakura General Hospital Stroke Center

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Other Title
  • CAS 後過灌流症候群の発症予測に関する研究

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Abstract

Objective: The purpose of our retrospective study was to find predictors of hyperperfusion syndrome (HPS) before and immediately after carotid artery stenting (CAS). Methods: Included for analysis were patients 1) who underwent elective CAS, 2) who underwent single-photon emission computed tomography (SPECT) and transcranial color-coded real-time sonography before and immediately after CAS. The ratio of cerebral blood flow (CBF) by comparing the CBF in the affected cerebral hemisphere area to the CBF in the ipsilateral cerebellar hemisphere (middle cerebral artery (MCA)-to-cerebellar activity ratio), cerebral vasoreactivity (CVR), MCA mean blood flow velocity in the affected hemisphere and MCA mean blood flow velocity ratio (preoperative to postoperative) were assessed. Results: Sixty-four patients who underwent elective CAS were analyzed retrospectively. Nine patients presented HPS. Logistic regression analysis showed that CVR (p<0.01) and MCA mean blood flow velocity (p<0.05) were the significant predictors among the pre-CAS variables, and that MCA mean blood flow velocity ratio (p<0.05) and MCA-to-cerebellar activity ratio change (p<0.05) were significant predictors among the post-CAS variables. Conclusions: SPECT and transcranial color-coded real-time sonography studies are useful in predicting HPS.

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