The impact of aging on the course of the azygos vein

  • SAITO Akira
    Department of Anatomy, Showa University School of Medicine Demartment of Gastroenterological and General Surgery, Showa University Hospital
  • MURAKAMI Masahiko
    Demartment of Gastroenterological and General Surgery, Showa University Hospital
  • TOMIOKA Kodai
    Department of Anatomy, Showa University School of Medicine Demartment of Gastroenterological and General Surgery, Showa University Hospital
  • EZURE Hiromitsu
    Department of Anatomy, Showa University School of Medicine
  • MORIYAMA Hiroshi
    Department of Anatomy, Showa University School of Medicine
  • MORI Ryoichi
    Department of Anatomy, Showa University School of Medicine
  • NAKAJIMA Koh
    Demartment of Oral Anatomy, Showa University School of Dentistry
  • NAKAMURA Masanori
    Demartment of Oral Anatomy, Showa University School of Dentistry
  • OTSUKA Naruhito
    Department of Anatomy, Showa University School of Medicine

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Introduction: The human azygos vein (AV) generally runs on the right side of the vertebral column. However, a shift in its course to the middle/left side of the vertebral column, potentially as a result of aging, has been reported. The aim of this study was to understand the relationship between AV displacement and aging. Materials and Methods: Forty-seven adult cadavers were dissected. When an AV left shift was observed, long axis AV length was measured by calculating the number of vertebral bodies under the vein. We also investigated whether a crossover vein existed between AV and hemiazygos vein at the extreme left shifting point, and whether osteophytes existed along the vertebral column. Results: Forty-four cadavers (94%) had left-shifted AVs. A weak positive correlation between age and the length of the left shift was observed (r = 0.3061, P = 0.0364). Thirty cadavers (64%) had crossover veins at the extreme left shifting point, and 24 cadavers (51%) had osteophytes along the vertebral column. There was no significant relationship between the length of left-shifted AVs and the existence of crossover veins or osteophytes. Conclusion: The possibility of AV displacement to the left as part of the aging process is suggested.

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