Diffuse Alveolar Hemorrhage Emerging One Week after Starting High-dose Corticosteroid Therapy for Granulomatosis with Polyangiitis (GPA) with Systemic Lupus Erythematosus (SLE)

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  • Fukui Shoichi
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Iwamoto Naoki
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Tsuji Sosuke
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Umeda Masataka
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Nishino Ayako
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Nakashima Yoshikazu
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Suzuki Takahisa
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Horai Yoshiro
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Koga Tomohiro
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Kawashiri Shin-ya
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan Department of Public Health, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Ichinose Kunihiro
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Hirai Yasuko
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Tamai Mami
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Nakamura Hideki
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Origuchi Tomoki
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan Department of Rehabilitation Sciences, Nagasaki University Graduate School of Biomedical Sciences, Japan
  • Kawakami Atsushi
    Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Japan

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抄録

A 69-year-old man was diagnosed with granulomatosis with polyangiitis (GPA) based on the presence of skin granuloma, refractory otitis media, renal insufficiency and myeloperoxidase-antineutrophil cytoplasmic antibody positivity and slight lung opacity. He was treated with high-dose corticosteroid therapy. Despite the initial improvement of his renal function and a decrease in his C-reactive protein level, he suffered from an alveolar hemorrhage one week after the start of corticosteroid therapy. An anti-dsDNA antibody test was positive and the patient had hypocomplementemia. Elements of both GPA and systemic lupus erythematosus were thought to have affected his clinical course.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 54 (20), 2681-2686, 2015

    一般社団法人 日本内科学会

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