<b>The Effectiveness of Shimotsuto Extract for Patients with Muscle C</b><b>ramp</b>

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  • ITO Takashi
    Institute of Oriental Medicine, Tokyo Women's Medical University
  • KIMURA Yoko
    Institute of Oriental Medicine, Tokyo Women's Medical University
  • OTA Shizuka
    Center of Japanese Oriental Medicine, Kasima Rosai Hospital, Japan Labour Health and Welfare Organization
  • YAMAMOTO Shohaku
    Center of Japanese Oriental Medicine, Kasima Rosai Hospital, Japan Labour Health and Welfare Organization
  • SUDA Norio
    Center of Japanese Oriental Medicine, Kasima Rosai Hospital, Japan Labour Health and Welfare Organization Department of General Medicine and Primary Care, University of Tsukuba Hospital
  • NAKAZAWA Kazuhiro
    Department of General Medicine and Primary Care, University of Tsukuba Hospital

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Other Title
  • <b>こむら返りに対する四物湯エキスの有用性</b>
  • 臨床報告 こむら返りに対する四物湯エキスの有用性
  • リンショウ ホウコク コムラカエリ ニ タイスル ヨンブツ トウ エキス ノ ユウヨウセイ

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Abstract

The effectiveness of the Kampo medicine shakuyakukanzoto extract for patients with muscle cramp is well known, but recently side effects related to pseudoaldosteronism have also been reported. To avoid this issue, Kampo medicines without Glycyrrhizae Radix are needed for treatment of muscle cramp. We investigated the therapeutic effect of shimotsuto extract, which has traditionally been used to treat anemia, in 26 patients (mean age : 70.7 ± 12.1 years) with muscle cramp. Improvement of the symptom was noted in 18 patients (69%), with no change in 8 patients (31%). The abdominal muscle tension of the former patients was significantly lower than the latter. Here, the cases of four representative patients in whom muscle cramp was improved by shimotsuto are described. The response rate to shimotsuto was similar to that of shakuyakukanzoto. Our results suggest that shimotsuto extract is a suitable alternative to shakuyakukanzoto for treatment of muscle cramp in older non-robust type patients not in need of emergency care.

Journal

  • Kampo Medicine

    Kampo Medicine 66 (3), 244-249, 2015

    The Japan Society for Oriental Medicine

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