Quantitative Assessment of Fluid Accumulation Using Bioelectrical Impedance Analysis in Patients With Acute Decompensated Heart Failure

• Sakaguchi Taiki

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Yasumura Kaori

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Nishida Hiroki

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Inoue Hiroyuki

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Furukawa Tetsuo

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Shinouchi Kazuya

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Miura Hiroyuki

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Miyazaki Koichi

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Hamano Gou

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Koide Masao

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Abe Haruhiko

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Date Motoo

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Hirooka Keiji

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Koretsune Yukihiro

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Kusuoka Hideo

  Division of Cardiology, National Hospital Organization Osaka National Hospital

• Yasumura Yoshio

  Division of Cardiology, National Hospital Organization Osaka National Hospital

抄録

Background:Acute decompensated heart failure (ADHF) is generally considered to be a problem of fluid volume overload, therefore accurately quantifying the degree of fluid accumulation is of critical importance in assessing whether adequate decongestion has been achieved. The aim of this study was to develop and validate a method to quantify the degree of fluid accumulation in patients with ADHF.Methods and Results:Using multi-frequency bioelectrical impedance analysis (BIA), we measured extracellular water (ECW) volume in 130 ADHF patients on admission and at discharge. We also predicted optimal ECW volume using original equations based on data from 60 control subjects without the signs of HF. Measured/predicted (M/P) ratio of ECW in ADHF patients was observed to decrease from 1.26±0.25 to 1.04±0.17 during hospitalization (P<0.001). The amount of ECW volume reduction was significantly correlated with reduction in body weight (r=0.766, P<0.001). On multivariate analysis, higher M/P ratio of ECW at discharge was associated with increased risk of ADHF readmission or cardiac death within 6 months after discharge.Conclusions:Multi-frequency BIA-measured ECW was found to offer valuable information for analyzing the pathophysiology of ADHF, and may be a useful guide in the management of this disease. (Circ J 2015; 79: 2616–2622)

収録刊行物

• Circulation Journal

  Circulation Journal 79 (12), 2616-2622, 2015

  一般社団法人 日本循環器学会

キーワード

• Acute heart failure
• Bioelectrical impedance analysis
• Fluid accumulation

詳細情報

• CRID: 1390001205107900416
• NII論文ID: 130005110904
• NII書誌ID: AA11591968
• DOI: 10.1253/circj.cj-15-0723
• ISSN: 13474820
• ISSN: 13469843
• NDL書誌ID: 026944398
• PubMed: 26477274
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I026944398
• Web Site: https://www.jstage.jst.go.jp/article/circj/79/12/79_CJ-15-0723/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2016232689
• 本文言語コード: en
• データソース種別:
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  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
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