Two cases of acute hepatitis E in the same geographical area infected with different viral strains

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  • Morita Susumu
    Department of Gastroenterology, National Hospital Organization, Shinshu Ueda Medical Center
  • Yoshizawa Kaname
    Department of Gastroenterology, National Hospital Organization, Shinshu Ueda Medical Center
  • Uchiyama Natsuki
    Department of Gastroenterology, National Hospital Organization, Shinshu Ueda Medical Center
  • Fujimori Kazuya
    Department of Gastroenterology, National Hospital Organization, Shinshu Ueda Medical Center
  • Shigeno Takashi
    Department of Gastroenterology, National Hospital Organization, Shinshu Ueda Medical Center
  • Okamoto Hiroaki
    Division of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine

Bibliographic Information

Other Title
  • 同一地区内で発症した遺伝子配列の異なるE型肝炎ウイルス株による急性肝炎の2例
  • ドウイツ チク ナイ デ ハッショウ シタ イデンシ ハイレツ ノ コトナル Eガタ カンエンウイルスカブ ニ ヨル キュウセイ カンエン ノ 2レイ

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Abstract

We recently encountered 2 cases of acute hepatitis E virus (HEV) infection occurring within a span of one year. Both patients resided within a radius of several kilometers of each other. Neither patients had eaten wild meat or uncooked pork. Phylogenetic analysis revealed that the two HEV strains were 3b/3jp but belonged to different lineages, which indicated that multiple HEV strains could have existed as a source of infection in the same area. HEV infection without any apparent symptoms may occur more commonly than previously believed. To prevent acute hepatitis E, further clarification of viral sources and routes is needed.

Journal

  • Kanzo

    Kanzo 56 (11), 625-627, 2015

    The Japan Society of Hepatology

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