動脈塞栓術が有効であった肝細胞癌蝶形骨洞転移例

  • 金井 理絵
    公益財団法人田附興風会医学研究所 北野病院耳鼻咽喉科・頭頸部外科
  • 田村 芳寛
    たむら耳鼻咽喉科
  • 前谷 俊樹
    公益財団法人田附興風会医学研究所 北野病院耳鼻咽喉科・頭頸部外科
  • 山下 勝
    公益財団法人田附興風会医学研究所 北野病院耳鼻咽喉科・頭頸部外科
  • 西田 明子
    公益財団法人田附興風会医学研究所 北野病院耳鼻咽喉科・頭頸部外科
  • 吉田 季来
    公益財団法人田附興風会医学研究所 北野病院耳鼻咽喉科・頭頸部外科
  • 金丸 眞一
    公益財団法人田附興風会医学研究所 北野病院耳鼻咽喉科・頭頸部外科

書誌事項

タイトル別名
  • A Case of Metastatic Hepatocellular Carcinoma to the Sphenoid Sinus Controlled by Transcatheter Arterial Embolization
  • 臨床 動脈塞栓術が有効であった肝細胞癌蝶形骨洞転移例
  • リンショウ ドウミャク ソクセンジュツ ガ ユウコウ デ アッタ カン サイボウ ガンチョウケイコツドウ テンイレイ

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抄録

Herein, we report a rare case of metastatic sphenoid sinus tumor from hepatocellular carcinoma (HCC). Transcatheter arterial embolization to treat the metastatic sinus tumor resulted in a marked reduction of the tumor size in this case.<br/>A 60-year-old male patient who had underwent several sessions of transcatheter arterial chemoembolization and radio-frequency ablation for multiple HCC, was referred to our department because of FDG accumulation detected in his left sphenoid sinus and portal lymph nodes by PET-CT. MRI and CT revealed surrounding bone destruction by the sphenoid sinus lesion. Although we attempted biopsy of the sphenoid sinus tumor under endoscopic guidance, sufficient tissue could not be obtained for diagnosis because of excessive bleeding. A subsequent angiography revealed that the tumor received good blood supply from the left maxillary artery, therefore, transcatheter arterial embolization of the maxillary artery with a platinum coil was performed to reduce potential bleeding during biopsy. On the day after the embolization, re-biopsy of the sphenoid sinus tumor was successfully performed without any significant bleeding. Since the obtained tissue revealed the same pathological features as the portal lymph nodes, the sphenoid sinus tumor was diagnosed as metastatic HCC.<br/>Two months after from the embolization procedure, a MRI scan revealed a reduction of the size of the sphenoid sinus tumor to less than 50% of its original size. A follow-up PET-CT after additional palliative chemoradiotherapy no longer showed FDG accumulation in the sphenoid sinus tumor. The sphenoid sinus tumor showed no re-growth nor was associated with any symptoms during 4.5 years, follow up period until the patient’s death, which was due to recurrence of the portal lymph node metastases and femoral bone metastases.<br/>It is suggested that the transcatheter arterial embolization for the metastatic sphenoid sinus tumor from HCC caused a reduction of the tumor size as well as minimized bleeding during a biopsy.

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