Postnatal development of the gastrin-releasing peptide system in the lumbosacral spinal cord controlling male reproductive function in rats
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- KATAYAMA Nao
- Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University
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- OTI Takumi
- Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University
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- TAKANAMI Keiko
- Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University
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- SAKAMOTO Tatsuya
- Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University
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- SAKAMOTO Hirotaka
- Ushimado Marine Institute (UMI), Graduate School of Natural Science and Technology, Okayama University
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抄録
A sexually dimorphic spinal gastrin-releasing peptide (GRP) system in the lumbosacral spinal cord, which projects to the lower spinal centers, controls erection and ejaculation in rats. However, little is known about the postnatal development of this system. In this study, we therefore examined the postnatal development of the male-dominant spinal GRP system and its sexual differentiation in rats using immunohistochemistry. Our results show that male-dominant expression of GRP is prominent from the onset of puberty and that sexually dimorphism persists into adulthood. These results suggest that androgen surge during male puberty plays an important role in the development and maintenance of the male-specific GRP function in the rat spinal cord.
収録刊行物
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- Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences
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Proceedings of the Japan Academy. Ser. B: Physical and Biological Sciences 92 (2), 69-75, 2016
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詳細情報 詳細情報について
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- CRID
- 1390282679123642368
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- NII論文ID
- 130005125606
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- NII書誌ID
- AA00785485
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- ISSN
- 13492896
- 03862208
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- NDL書誌ID
- 027162465
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- PubMed
- 26860455
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可