Post-Transplant Membranous Nephropathy Associated with Chronic Active Antibody-Mediated Rejection and Hepatitis C Infection after Deceased Donor Renal Transplantation

DOI Web Site PubMed 参考文献21件 オープンアクセス
  • Doke Tomohito
    Department of Nephrology, Fujita Health University School of Medicine, Japan
  • Sato Waichi
    Department of Nephrology, Fujita Health University School of Medicine, Japan
  • Takahashi Kazuo
    Department of Nephrology, Fujita Health University School of Medicine, Japan
  • Hayashi Hiroki
    Department of Nephrology, Fujita Health University School of Medicine, Japan
  • Koide Sigehisa
    Department of Nephrology, Fujita Health University School of Medicine, Japan
  • Sasaki Hitomi
    Department of Urology, Fujita Health University School of Medicine, Japan
  • Kusaka Mamoru
    Department of Urology, Fujita Health University School of Medicine, Japan
  • Shiroki Ryoichi
    Department of Urology, Fujita Health University School of Medicine, Japan
  • Hoshinaga Kiyotaka
    Department of Urology, Fujita Health University School of Medicine, Japan
  • Takeda Asami
    Kidney Center, Japanese Red Cross Nagoya Daini Hospital, Japan
  • Yuzawa Yukio
    Department of Nephrology, Fujita Health University School of Medicine, Japan
  • Hasegawa Midori
    Department of Nephrology, Fujita Health University School of Medicine, Japan

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抄録

A 53-year-old woman who had undergone deceased donor kidney transplantation twice, at 35 and 43 years of age, presented with renal impairment. She was infected with hepatitis C virus (HCV). The histology of the graft kidney revealed post-transplant membranous nephropathy (MN) with podocytic infolding and antibody-mediated rejection (AMR). IgG subclass staining showed fine granular deposits of IgG1 and IgG3, but not IgG4, in the glomerular capillary walls. Panel reactive antibody scores for human leukocyte antigen class I and class II were 92.67% and 66.68%, respectively. Thus, this case of post-transplanted MN was considered to be associated with AMR and HCV infection.<br>

収録刊行物

  • Internal Medicine

    Internal Medicine 55 (4), 375-380, 2016

    一般社団法人 日本内科学会

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