Cardiovascular Instability Preceded by Orolingual Angioedema after Alteplase Treatment
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- Kageyama Takashi
- Department of Neurology, Tenri Hospital, Japan
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- Okanoue Yusuke
- Department of Otolaryngology, Tenri Hospital, Japan
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- Takai Rieko
- Department of General Internal Medicine, Tenri Hospital, Japan
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- Suenaga Toshihiko
- Department of Neurology, Tenri Hospital, Japan
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抄録
An 87-year-old man taking antihypertensive medications, including 10 mg enalapril, daily visited our hospital complaining of motor aphasia, dysarthria, and right hemiparesis. Magnetic resonance imaging revealed an ischemic lesion in the left frontal lobe including the insular cortex and severe stenosis of the left middle cerebral artery. After he received intravenous alteplase infusion, he developed orolingual angioedema followed by transient bradycardia with subsequent hypotension, resulting in the deterioration of his neurological signs and expansion of the ischemic lesion. Orolingual angioedema after intravenous alteplase infusion may follow cardiovascular instability and disease progression in stroke patients.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 55 (4), 409-412, 2016
一般社団法人 日本内科学会