-
- Takada Shimon
- Department of General Internal Medicine, Nara City Hospital, Japan
-
- Fujiwara Sho
- Department of Medicine, Tohoku University School of Medicine, Japan
-
- Inoue Toshiya
- Urasoe General Hospital, Japan
-
- Kataoka Yuki
- Hyogo Prefectural Amagasaki Hospital, Japan
-
- Hadano Yoshiro
- Rakuwakai Otowa Hospital, Japan
-
- Matsumoto Kentaro
- National Medical Clinic, Japan
-
- Morino Kyoko
- Department of Medicine, Tohoku University School of Medicine, Japan
-
- Shimizu Taro
- Division of General Internal Medicine, Tokyo Joto Hospital, Japan
この論文をさがす
抄録
We mainly refer to the acute setting of meningococcemia. Meningococcemia is an infection caused by Neisseria meningitidis, which has 13 clinically significant serogroups that are distinguishable by the structure of their capsular polysaccharides. N. meningitidis, also called meningococcus, is a Gram-negative, aerobic, diplococcus bacterium. The various consequences of severe meningococcal sepsis include hypotension, disseminated intravascular coagulation (DIC), multiple organ failure, and osteonecrosis due to DIC. The gold standard for the identification of meningococcal infection is the bacteriologic isolation of N. meningitidis from body fluids such as blood, cerebrospinal fluid (CSF), synovial fluid, and pleural fluid. Blood, CSF, and skin biopsy cultures are used for diagnosis. Meningococcal infection is a medical emergency that requires antibiotic therapy and intensive supportive care. Management of the systemic circulation, respiration, and intracranial pressure is vital for improving the prognosis, which has dramatically improved since the wide availability of antibiotics. This review of the literature provides an overview of current concepts on meningococcemia due to N. meningitidis infection.<br>
収録刊行物
-
- Internal Medicine
-
Internal Medicine 55 (6), 567-572, 2016
一般社団法人 日本内科学会