Markovnikov-Selective Addition of Fluorous Solvents to Unactivated Olefins Using a Co Catalyst

• Shigehisa Hiroki

  Department of Pharmacy, Musashino University

• Kikuchi Harue

  Department of Pharmacy, Musashino University

• Hiroya Kou

  Department of Pharmacy, Musashino University

抄録

We developed an addition reaction of fluorous solvents to olefins using salen–cobalt (Co) complex, N-fluoro-2,4,6-trimethylpyridinium tetrafluoroborate, and 1,1,3,3-tetramethyldisiloxane. This reaction condition was found to activate olefins, which enabled them to be attacked by 2,2,2-trifluoroethanol (TFE) and 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), both of which are electronically weak nucleophiles.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 64 (4), 371-374, 2016

  公益社団法人 日本薬学会

キーワード

• hydroalkoxylation
• cobalt (Co)
• fluorous solvent
• olefin

詳細情報

• CRID: 1390282679153954176
• NII論文ID: 130005141025
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.c15-01024
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 027220977
• PubMed: 27039835
• Web Site: http://id.ndl.go.jp/bib/027220977
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I027220977
• Web Site: https://www.jstage.jst.go.jp/article/cpb/64/4/64_c15-01024/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可