Postprandial Reactive Hypoglycemia Treated with a Low-dose Alpha-glucosidase Inhibitor: Voglibose May Suppress Oxidative Stress and Prevent Endothelial Dysfunction
-
- Suzuki Kunihiro
- Department of Endocrinology and Metabolism, Dokkyo Medical University, Japan
-
- Katsura Daisuke
- Department of Endocrinology and Metabolism, Dokkyo Medical University, Japan
-
- Sagara Masaaki
- Department of Endocrinology and Metabolism, Dokkyo Medical University, Japan
-
- Aoki Chie
- Department of Endocrinology and Metabolism, Dokkyo Medical University, Japan
-
- Nishida Mai
- Department of Endocrinology and Metabolism, Dokkyo Medical University, Japan
-
- Aso Yoshimasa
- Department of Endocrinology and Metabolism, Dokkyo Medical University, Japan
この論文をさがす
抄録
We encountered a 62-year-old woman who experienced frequent episodes of hypoglycemia. She was diagnosed with postprandial reactive hypoglycemia according to the results of oral glucose and sucrose tolerance tests, having undergone an endocrinological examination and image inspection. The administration of low-dose voglibose, an alpha-glucosidase inhibitor (α-GI), improved the glucose fluctuations and inhibited hypoglycemic symptoms. Voglibose is also known to diminish oxidative stress and maintain endothelial function after hyperglycemia. An α-GI might effectively prevent hypoglycemic symptoms and endothelial dysfunction by suppressing oxidative stress in such cases.<br>
収録刊行物
-
- Internal Medicine
-
Internal Medicine 55 (8), 949-953, 2016
一般社団法人 日本内科学会