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- Takahashi Kentaro
- Research Center for Allergy and Clinical Immunology, Asahi General Hospital, Japan
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- Kagami Shin-ichiro
- Research Center for Allergy and Clinical Immunology, Asahi General Hospital, Japan
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- Kawashima Hirotoshi
- Research Center for Allergy and Clinical Immunology, Asahi General Hospital, Japan
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- Kashiwakuma Daisuke
- Research Center for Allergy and Clinical Immunology, Asahi General Hospital, Japan
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- Suzuki Yoshio
- Department of Pathology, Asahi General Hospital, Japan
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- Iwamoto Itsuo
- Research Center for Allergy and Clinical Immunology, Asahi General Hospital, Japan
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抄録
We herein describe a second Japanese case of sarcoidosis presenting Addison's disease. A 52-year-old man was diagnosed with sarcoidosis based on clinical and laboratory findings, including bilateral hilar lymphadenopathy and elevated levels of serum angiotensin-converting enzyme and lysozyme, as well as the presence of noncaseating epithelioid granulomas. The patient also exhibited general fatigue, pigmentation, weight loss, hypotension and hyponatremia, suggestive of chronic adrenocortical insufficiency. An endocrine examination confirmed primary adrenocortical insufficiency. This case suggests the direct involvement of sarcoid granuloma in the adrenal glands.<br>
収録刊行物
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- Internal Medicine
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Internal Medicine 55 (9), 1223-1228, 2016
一般社団法人 日本内科学会