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- 伊藤 幸成
- 理化学研究所
書誌事項
- タイトル別名
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- Encounter with Carbohydrate Chemistry to Amateurish Glycobiology
- トウシツ カガク エ ノ デアイ カラ シロウト シゴト ノ トウサ セイブツガク エ
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抄録
Carbohydrates are important constituents of biomolecules and natural products. In particular, glycoproteins, glycolipids, proteoglycans and cell-surface glycoconjugates are known to play various roles in biologically important phenomena. In spite of that, precise analysis of their functions has been hindered by their structural diversity and complexity. Synthetic organic chemistry is considered to be powerful in solving problems associated with their biological functions. Under such circumstances, major part of research in our group has been directed to the synthesis and functional analysis of glycoconjugate oligosaccharides of various origins. This account aims to summarize my research history in carbohydrate chemistry, which mainly covers 1) development of methodologies for oligosaccharide synthesis, 2) approaches to stereoselective glycoside bond formation, 3) synthetic studies on glycoconjugate glycan chains, and 4) analyses of glycoprotein processing and protein quality control system, and 5) studies on carbohydrate binding natural products.
収録刊行物
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- 有機合成化学協会誌
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有機合成化学協会誌 74 (3), 206-218, 2016
公益社団法人 有機合成化学協会
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詳細情報 詳細情報について
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- CRID
- 1390282680318359808
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- NII論文ID
- 130005151890
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- NII書誌ID
- AN0024521X
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- ISSN
- 18836526
- 00379980
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- NDL書誌ID
- 027188897
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
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- 抄録ライセンスフラグ
- 使用不可