The current management of cholangiocarcinoma: A comparison of current guidelines

  • Cai Yulong
    Department of Bile Duct Surgery, West China Hospital, Sichuan University Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo
  • Cheng Nansheng
    Department of Bile Duct Surgery, West China Hospital, Sichuan University
  • Ye Hui
    Department of Bile Duct Surgery, West China Hospital, Sichuan University
  • Li Fuyu
    Department of Bile Duct Surgery, West China Hospital, Sichuan University
  • Song Peipei
    Graduate School of Frontier Sciences, The University of Tokyo
  • Tang Wei
    Department of Bile Duct Surgery, West China Hospital, Sichuan University Hepato-Biliary-Pancreatic Surgery Division, Department of Surgery, Graduate School of Medicine, The University of Tokyo

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Cholangiocarcinoma (CC) accounts for about 3% of all gastrointestinal tumors and is the second most common primary liver tumor. Quality guidelines on CC are needed to guide hepatobiliary surgeons. Here, current guidelines on CC were reviewed to provide useful information and suggestions to help institutes and organizations all around the world to draft better guidelines on CC. Literature databases were electronically searched to identify guidelines or consensus statements regarding CC published from 2002-2016. Nine guidelines were included in this review. Comparison of the current guidelines revealed several inconsistencies. Signs of conflicting views indicated a lack of high level evidence. More studies need to be conducted in areas of contention to help update the guidelines. Organizations and medical societies need to be encouraged to use standard evaluation measures, to restrict tumors to CC or iCC, pCC, or dCC specifically, to give recommendations in accordance with the equipment that is available for diagnosis and treatment in different counties, and to use an appropriate and consistent structure when establishing and drafting guidelines for CC.

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  • BioScience Trends

    BioScience Trends 10 (2), 92-102, 2016

    特定非営利活動法人 バイオ&ソーシャル・サイエンス推進国際研究交流会

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