当科における若年者口腔癌25年間の臨床統計的検討

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  • Clinical statistical study of oral cancer in young patients during 25 years in our department
  • トウ カ ニ オケル ジャクネンシャ コウコウ ガン 25ネンカン ノ リンショウ トウケイテキ ケントウ

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The number of patients with oral cancer is tending to increase in Japan. It has been reported that oral cancer is most highly prevalent in men 60 years or older. However, the number of the affected young patients and female patients has tended to increase in recent years. Thirty-eight patients 40 years or younger (young patients) with oral cancer, treated primarily at Tokyo Dental College Chiba Hospital from 1987 through 2012, were retrospectively studied. Among a total of 758 patients with oral cancer treated in our department during this period, young patients comprised 5%. The ratio of young patients with oral cancer significantly increased during the 25 years. The male-female ratio of young patients was 1.38:1, while that of the other patients was 1.41:1. The tongue was the most frequency encountered primary site among young patients, accounting for 76.3% of cases. Well-differentiated type was most common, accounting for 39.5%, on histopathological differentiation typing. The incidences of stage I, II, III, and IV oral cancer according to the TNM staging system were 28.9%, 23.7%, 23.7%, and 23.7%, respectively. The 5-year overall survival rate was 94.3%. The 5-year disease-free survival rate was 88.2%. The survival rate of young patients did not differ significantly from that of the other patients, although outcomes were slightly more favorable among young patients than other patients.

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