Yezo'otogirins D-H, Acylphloroglucinols and Meroterpenes from Hypericum yezoense

• Tanaka Naonobu

  Graduate School of Pharmaceutical Sciences, Hokkaido University Graduate School of Pharmaceutical Sciences, Tokushima University

• Tsuji Eri

  Graduate School of Pharmaceutical Sciences, Hokkaido University

• Kashiwada Yoshiki

  Graduate School of Pharmaceutical Sciences, Tokushima University

• Kobayashi Jun’ichi

  Graduate School of Pharmaceutical Sciences, Hokkaido University

書誌事項

タイトル別名

• Yezo’otogirins D–H, Acylphloroglucinols and Meroterpenes from <i>Hypericum yezoense</i>

抄録

Investigation of the methanolic extract from the aerial parts of Hypericum yezoense resulted in the isolation of three new acylphloroglucinols, yezo’otogirins D–F (1–3), and two new meroterpenes, yezo’otogirins G (4) and H (5). The structures of 1–5 were assigned on the basis of spectroscopic data. Yezo’otogirin D (1) is an acylphloroglucinol with a monoterpene moiety linked through an ether bond, while yezo’otogirins E (2) and F (3) are polyprenylated acylphloroglucinols possessing a tricyclic core. Yezo’otogirins G (4) and H (5) are linear meroterpenes with an enolized β-diketone moiety. Yezo’otogirin E (2) exhibited antimicrobial activity against Escherichia coli and Staphylococcus aureus.

収録刊行物

• ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ

  ＣＨＥＭＩＣＡＬ　＆　ＰＨＡＲＭＡＣＥＵＴＩＣＡＬ　ＢＵＬＬＥＴＩＮ 64 (7), 991-995, 2016

  公益社団法人 日本薬学会

キーワード

• acylphloroglucinol
• meroterpene
• <i>Hypericum yezoense</i>
• yezo’otogirin

詳細情報

• CRID: 1390282679155485696
• NII論文ID: 130005160022
• NII書誌ID: AA00602100
• DOI: 10.1248/cpb.c16-00243
• ISSN: 13475223
• ISSN: 00092363
• NDL書誌ID: 027451861
• PubMed: 27373661
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I027451861
• Web Site: https://www.jstage.jst.go.jp/article/cpb/64/7/64_c16-00243/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• 抄録ライセンスフラグ: 使用不可