Hyponatremic Chloride-depletion Metabolic Alkalosis Successfully Treated with High Cation-gap Amino Acid
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- Ryuge Akihiro
- Department of Nephrology and Hypertension, St. Marianna University School of Medicine, Japan Department of Nephrology, Chubu-Rosai Hospital, Japan
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- Matsui Katsuomi
- Department of Nephrology and Hypertension, St. Marianna University School of Medicine, Japan
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- Shibagaki Yugo
- Department of Nephrology and Hypertension, St. Marianna University School of Medicine, Japan
抄録
Chloride (Cl)-depletion alkalosis (CDA) develops due to the loss of Cl-rich body fluid, i.e., vomiting or diuretics use, and is typically treated with a chloride-rich solution such as normal saline (NS). Although NS is one of the most utilized Cl-rich solutions, high cation-gap amino acid (HCG-AA) predominantly comprises Cl and less sodium, making HCG-AA more efficient in correcting CDA. We herein report a case of CDA with chronic hyponatremia after frequent vomiting, which was successfully treated with HCG-AA without overcorrecting hyponatremia or causing hypervolemia. HCG-AA may be more beneficial than NS for treating hyponatremic or hypervolemic metabolic alkalosis.
収録刊行物
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- Internal Medicine
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Internal Medicine 55 (13), 1765-1767, 2016
一般社団法人 日本内科学会
