Time-Series Analysis Comparing the Prevalence of Antibodies against Nine Viral Species Found in Umbilical Cord Blood in Japan
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- Takemoto Koji
- Department of Pediatrics, Konan Kosei Hospital
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- Nishimura Naoko
- Department of Pediatrics, Konan Kosei Hospital
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- Kozawa Kei
- Department of Pediatrics, Konan Kosei Hospital
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- Hibino Hiromi
- Department of Pediatrics, Konan Kosei Hospital
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- Kawaguchi Masahiro
- Department of Pediatrics, Konan Kosei Hospital
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- Takeuchi Suguru
- Department of Pediatrics, Konan Kosei Hospital
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- Fujishiro Naozumi
- Department of Pediatrics, Konan Kosei Hospital
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- Arai Sakiko
- Department of Pediatrics, Konan Kosei Hospital
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- Gotoh Kensei
- Department of Pediatrics, Konan Kosei Hospital
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- Hosono Haruki
- Department of Pediatrics, Konan Kosei Hospital
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- Ozaki Takao
- Department of Pediatrics, Konan Kosei Hospital
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抄録
In this study, we investigated the prevalence of antibodies against 9 viral species found in umbilical cord blood from 561 neonates in 2013. Serum IgG antibodies against the following viruses were measured: herpes simplex virus (HSV), varicella-zoster virus (VZV), Epstein-Barr virus (EBV), cytomegalovirus (CMV), human herpesvirus 6 (HHV-6), measles virus (MV), rubella virus (RV), mumps virus (MuV), and human parvovirus B19 (HPV B19). A survey questionnaire regarding past medical history and maternal immunization status for the vaccine-preventable diseases of varicella, measles, rubella, and mumps was simultaneously administered. The results were compared with previous data collected in 2001–2002 from 378 umbilical cord blood samples. Viral seroprevalence data were: HSV, 54%; VZV, 96%; EBV, 96%; CMV, 67%; HHV-6, 100%; MV, 95%; RV, 94%; MuV, 64%; and HPV B19, 55%. The seroprevalence of CMV, MV, and MuV were significantly lower in 2013 than in 2001–2002 (CMV, 76%; MV, 98%; MuV, 93%). Compared with the 2001–2002 data, the mean IgG antibody values of the 4 vaccine-preventable diseases were significantly lower, and vaccination coverage for those diseases among mothers was significantly higher. Thus, attention should be paid to antibody levels in women of childbearing age in the future.
収録刊行物
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- Japanese Journal of Infectious Diseases
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Japanese Journal of Infectious Diseases 69 (4), 314-318, 2016
国立感染症研究所 Japanese Journal of Infectious Diseases 編集委員会
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詳細情報 詳細情報について
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- CRID
- 1390282681217568128
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- NII論文ID
- 130005165486
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- NII書誌ID
- AA1132885X
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- ISSN
- 18842836
- 13446304
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- NDL書誌ID
- 027506921
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- PubMed
- 26567842
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可