Relation between VE/VCO2 slope and maximum phonation time in chronic heart failure patients

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【Purpose】This study aimed to determine the relation between the regression slope relating minute ventilation to carbon dioxide output(VE/VCO2 slope)and maximum phonation time(MPT), and the MPT required to attain a threshold value for VE/VCO2 slope of ≤34 in chronic heart failure(CHF)patients.【Methods】This cross-sectional study enrolled 115 CHF patients(mean age, 54.5 years;men, 84.9%). VE/VCO2 slope was assessed during cardiopulmonary exercise testing(CPX). Thereafter, patients were divided into two groups according to exercise capacity:VE/VCO2 slope ≤34(VE/VCO2 ≤34 group, n=81)and VE/VCO2 slope>34(VE/VCO2>34 group, n=34). For MPT measurements, all patients produced a sustained vowel/a:/for as long as possible during respiratory effort from a the seated position.【Results】All subjects showed significant negative correlation between VE/VCO2 slope and MPT(r=-0.51, P<.001). After adjustment for clinical characteristics, MPT was significantly higher in the VE/VCO2 ≤34 group versus VE/VCO2>34 group(21.4±6.4 vs. 17.4±4.3 sec, F=7.4, P=.007). The appropriate MPT cut-off value for identifying a VE/VCO2 slope ≤34 was 18.12 sec.【Discussion】An MPT value of 18.12 sec may be a useful target value for identifying CHF patients with a VE/VCO2 slope ≤34 and for risk management in these patients.

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詳細情報 詳細情報について

  • CRID
    1390282680552658304
  • NII論文ID
    130005247700
  • DOI
    10.14900/cjpt.2014.0016
  • 本文言語コード
    ja
  • データソース種別
    • JaLC
    • CiNii Articles
  • 抄録ライセンスフラグ
    使用不可

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