Successful Treatment of <i>Aspergillus</i> Empyema Using Open Window Thoracostomy Salvage Treatment and the Local Administration of an Antifungal Agent
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- Ashizawa Nobuyuki
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan Department of Clinical Infectious Diseases, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Japan
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- Nakamura Shigeki
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Japan
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- Ide Shotaro
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan
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- Tashiro Masato
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan Unit of Molecular Microbiology and Immunology, Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan
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- Takazono Takahiro
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan Unit of Molecular Microbiology and Immunology, Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan
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- Imamura Yoshifumi
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan Unit of Molecular Microbiology and Immunology, Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan
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- Miyazaki Taiga
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan Unit of Molecular Microbiology and Immunology, Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan
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- Izumikawa Koichi
- Unit of Molecular Microbiology and Immunology, Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Japan
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- Yamamoto Yoshihiro
- Department of Clinical Infectious Diseases, Toyama University Graduate School of Medicine and Pharmaceutical Sciences, Japan
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- Yanagihara Katsunori
- Department of Laboratory Medicine, Nagasaki University Hospital, Japan
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- Miyazaki Yoshitsugu
- Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases, Japan
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- Kohno Shigeru
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan
抄録
<p>A 76-year-old woman received long-term immunosuppressive treatment for collagen vascular disease-associated interstitial pneumonia. The patient developed a cavitary mass lesion in the right lower lung field, and both nontuberculous mycobacteria and Aspergillus spp. were isolated after bronchial washing. The patient underwent a right lower lobectomy but developed Aspergillus empyema. Empyema due to Aspergillus spp. is a rare and life-threatening condition; however, the standard therapeutic strategies for treating Aspergillus empyema are not clear. We herein report a case of Aspergillus empyema that was successfully treated with a combination therapy which included open-window thoracostomy and the administration of antifungal agents (systemic micafungin and local amphotericin-B). </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 55 (15), 2093-2099, 2016
一般社団法人 日本内科学会
