免疫抑制薬の後発医薬品使用に関する一考察

DOI
  • 本間 真人
    筑波大学医学医療系臨床薬剤学 筑波大学附属病院薬剤部

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タイトル別名
  • Generic substitution of immunosuppressive drugs - a point of view

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抄録

Ministry of health, labour and welfare of Japan is promoting the use of generic drugs in the DPC (diagnosis procedure combination) hospitals including medical institutions dealing with organ transplantation. Immunosuppressive agents of which blood concentration monitoring is recommended to optimize the individual dose in the transplant recipients are also required to substitute from original bland to generic one, even though their pharmacokinetics are not equal. In this paper, author describes several issues for generic substitution for immunosuppressive agents in the pharmacokinetic points of view. The ESOT (Europian Society Organ Transplantation) guideline for the generic substitution of immunosuppressive agents is also presented to discuss the proper use of the generic drugs for transplant recipients in Japan.

収録刊行物

  • Organ Biology

    Organ Biology 23 (2), 150-153, 2016

    一般社団法人　日本臓器保存生物医学会

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