Mycobacterium shigaense causes lymph node and cutaneous lesions as immune reconstitution syndrome in an AIDS patient: the third case report of a novel strain non-tuberculous Mycobacterium

  • Koizumi Yusuke
    Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Japan Department of Gastroenterology and Hematology, Shiga University of Medical Science, Japan
  • Shimizu Kaoru
    Department of Laboratory Medicine, Shiga University of Medical Science, Japan
  • Shigeta Masayo
    Department of Laboratory Medicine, Shiga University of Medical Science, Japan
  • Minamiguchi Hitoshi
    Department of Gastroenterology and Hematology, Shiga University of Medical Science, Japan
  • Hodohara Keiko
    Department of Gastroenterology and Hematology, Shiga University of Medical Science, Japan
  • Andoh Akira
    Department of Gastroenterology and Hematology, Shiga University of Medical Science, Japan
  • Tanaka Toshihide
    Department of Dermatology, Shiga University of Medical Science, Japan
  • Chikamatsu Kinuyo
    Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Japan
  • Mitarai Satoshi
    Department of Mycobacterium Reference and Research, Research Institute of Tuberculosis, Japan Anti-Tuberculosis Association, Japan
  • Mikamo Hiroshige
    Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Japan

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タイトル別名
  • <i>Mycobacterium shigaense</i> Causes Lymph Node and Cutaneous Lesions as Immune Reconstitution Syndrome in an AIDS Patient: The Third Case Report of a Novel Strain Non-tuberculous Mycobacterium

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抄録

<p>A 40-year-old man complaining of progressive body weight loss was diagnosed to have acquired immunodeficiency syndrome. Within 2 weeks after the initiation of combination antiretroviral therapy, he developed fever, massive cervical lymphadenopathy and a protruding subcutaneous abscess. A lymph node biopsy and abscess drainage revealed non-caseous granuloma and mycobacterium. The mycobacterium belonged to Runyon II group, but it showed no matches to any previously reported species. According to sequence analyses, the strain was identified as Mycobacterium shigaense. After six months of antimycobacterial treatment, the lesions were all successfully cured. This is the third case report of the novel mycobacterium, M. shigaense, presenting in associatioin with immune reconstitution syndrome. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 55 (22), 3375-3381, 2016

    一般社団法人 日本内科学会

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