Suspected Pulmonary Infection with <i>Trichoderma longibrachiatum</i> after Allogeneic Stem Cell Transplantation

  • Akagi Tomoaki
    Department of Hematology, Aomori Prefectural Central Hospital, Japan
  • Kawamura Chizuko
    Department of Pathology and Clinical Laboratories, Aomori Prefectural Central Hospital, Japan
  • Terasawa Norio
    Department of Pathology and Clinical Laboratories, Aomori Prefectural Central Hospital, Japan
  • Yamaguchi Kohei
    Department of Hematology, Aomori Prefectural Central Hospital, Japan
  • Kubo Kohmei
    Department of Hematology, Aomori Prefectural Central Hospital, Japan

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抄録

<p>Aspergillus and Candida species are the main causative agents of invasive fungal infections in immunocompromised human hosts. However, saprophytic fungi are now increasingly being recognized as serious pathogens. Trichoderma longibrachiatum has recently been described as an emerging pathogen in immunocompromised patients. We herein report a case of isolated suspected invasive pulmonary infection with T. longibrachiatum in a 29-year-old man with severe aplastic anemia who underwent allogeneic stem cell transplantation. A direct microscopic examination of sputum, bronchoaspiration, and bronchoalveolar lavage fluid samples revealed the presence of fungal septate hyphae. The infection was successfully treated with 1 mg/kg/day liposomal amphotericin B. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 56 (2), 215-219, 2017

    一般社団法人 日本内科学会

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