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- Kobernick Aaron K.
- Department of Allergy and Immunology, University of North Carolina School of Medicine
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- Burks A. Wesley
- Department of Pediatrics, University of North Carolina School of Medicine
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<p>Food allergy has grown in rapidly in prevalence, currently affecting 5% of adults and 8% of children. Management strategy is currently limited to 1) food avoidance and 2) carrying and using rescue intra- muscular epinephrine/adrenaline and oral antihistamines in the case of accidental ingestion; there is no FDA approved treatment. Recently, oral, sublingual and epicutaneous immunotherapy have been developed as active treatment of food allergy, though none have completed phase 3 study. Efficacy and safety studies of immunotherapy have been variable, though there is clearly signal that immunotherapy will be a viable option to desensitize patients. The use of bacterial adjuvants, anti-IgE monoclonal an- tibodies, and Chinese herbal formulations either alone or in addition to immunotherapy may hold promise as future options for active treatment. Active prevention of food allergy through early intro- duction of potentially offending foods in high-risk infants will be an important means to slow the rising incidence of sensitization.</p>
収録刊行物
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- Allergology International
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Allergology International 65 (4), 388-395, 2016
一般社団法人日本アレルギー学会
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詳細情報 詳細情報について
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- CRID
- 1390282679608149888
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- NII論文ID
- 130005431303
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- ISSN
- 14401592
- 13238930
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- 本文言語コード
- en
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- データソース種別
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- JaLC
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- CiNii Articles
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