Fluctuation of Dynamic Diastolic Function Relative to Static Cardiac Structure ― New Insights Into the Underlying Mechanism of Heart Failure With Preserved Ejection Fraction in Elderly Patients ―
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- Hoshida Shiro
- Department of Cardiovascular Medicine, Yao Municipal Hospital
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- Shinoda Yukinori
- Department of Cardiovascular Medicine, Yao Municipal Hospital
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- Ikeoka Kuniyasu
- Department of Cardiovascular Medicine, Yao Municipal Hospital
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- Minamisaka Tomoko
- Department of Cardiovascular Medicine, Yao Municipal Hospital
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- Fukuoka Hidetada
- Department of Cardiovascular Medicine, Yao Municipal Hospital
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- Inui Hirooki
- Department of Cardiovascular Medicine, Yao Municipal Hospital
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- Watanabe Tetsuya
- Department of Cardiovascular Medicine, Yao Municipal Hospital
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<p>Background:The mechanisms of heart failure with preserved ejection fraction (HFpEF) need to be clarified immediately.</p><p>Methods and Results:We examined diastolic function relative to arterial elasticity among hypertensive patients with preserved EF. Diastolic elastance (EdI)/effective arterial elastance (EaI), EdI/EaI=E/e’/(0.9×systolic blood pressure [SBP]) was significantly more impaired in women than in men among patients ≥75 years. The higher EdI/EaI value in elderly women implies they are intermittently exposed to higher left ventricular filling pressure relative to SBP during daily life.</p><p>Conclusions:Highly fluctuating impairment of diastolic function relative to arterial elasticity may predispose elderly women to pulmonary edema.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 81 (5), 755-758, 2017
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390001205108658176
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- NII論文ID
- 130005612061
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 028129769
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- PubMed
- 28132965
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可