Proton Beam Therapy for Pediatric Brain Tumor
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- MIZUMOTO Masashi
- Department of Radiation Oncology, University of Tsukuba
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- OSHIRO Yoshiko
- Department of Radiation Oncology, University of Tsukuba Department of Radiation Oncology, Tsukuba Medical Center Hospital
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- YAMAMOTO Tetsuya
- Department of Neurosurgery, University of Tsukuba
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- KOHZUKI Hidehiro
- Department of Neurosurgery, University of Tsukuba
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- SAKURAI Hideyuki
- Department of Radiation Oncology, University of Tsukuba
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<p>Cancer is a major cause of childhood death, with central nervous system (CNS) neoplasms being the second most common pediatric malignancy, following hematological cancer. Treatment of pediatric CNS malignancies requires multimodal treatment using a combination of surgery, chemotherapy, and radiotherapy, and advances in these treatments have given favorable results and longer survival. However, treatment-related toxicities have also occurred, particularly for radiotherapy, after which secondary cancer, reduced function of irradiated organs, and retarded growth are significant problems. Proton beam therapy (PBT) is a particle radiotherapy with excellent dose localization that permits treatment of liver and lung cancer by administration of a high dose to the tumor while minimizing damage to surrounding normal tissues. Thus, PBT has the potential advantages for pediatric cancer. In this context, we review the current knowledge on PBT for treatment of pediatric CNS malignancies.</p>
収録刊行物
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- Neurologia medico-chirurgica
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Neurologia medico-chirurgica 57 (7), 343-355, 2017
一般社団法人 日本脳神経外科学会
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詳細情報 詳細情報について
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- CRID
- 1390001205058638592
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- NII論文ID
- 130005773890
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- NII書誌ID
- AN00358613
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- ISSN
- 13498029
- 04708105
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- HANDLE
- 2241/00150322
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- PubMed
- 28603224
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- Crossref
- PubMed
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可