The relationship between age of onset and risk factors including family history and life style in Korean population with type 2 diabetes mellitus

DOI Web Site 参考文献21件
  • Noh Jin-Won
    Department of Healthcare Management, College of Health Science, Eulji University: 553 Sansung-daero, Soojung-gu, Sungnam-si, Kyungki-do 461-815, Republic of Korea Department of Health Sciences, Global Health, University Medical Centre Groningen/University of Groningen, The Netherlands
  • Jung Jin Hee
    Department of Nursing, Diabetes Education Team, Seoul National University Bundang Hospital, Republic of Korea
  • Park Jeong Eun
    Cheil General Hospital & Women’s Healthcare Center, College of Medicine, Dankook University, Republic of Korea
  • Lee Jung Hwa
    Diabetes Center, Kyung Hee University Hospital at Gangdong, Republic of Korea
  • Sim Kang Hee
    Diabetes Education Unit, Samsung Medical Center, Republic of Korea
  • Park Jumin
    National Institutes of Health Clinical Center, USA
  • Kim Min Hee
    Department of Physical Therapy, College of Health Science, Eulji University, Republic of Korea
  • Yoo Ki-Bong
    Department of Healthcare Management, College of Health Science, Eulji University: 553 Sansung-daero, Soojung-gu, Sungnam-si, Kyungki-do 461-815, Republic of Korea

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<p> [Purpose] The purpose of the present study was to assess the relationship between age of onset and risk factors including family history and life style in Korean population with type 2 diabetes mellitus (T2D). [Subjects and Methods] Subjects with T2D patients who received outpatient care for blood sugar control were randomly sampled at 13 general hospitals and 969 subjects were included. Cox proportional hazard models were used to confirm associations between age of onset and risk factors including family history and life style in Korean population with T2D. [Results] Parent history of T2D was significantly associated with age of onset. Compared to none of family members with T2D, those whose both father and mother had a history showed the highest the risk of early-onset (HR=2.36; 95% CI=1.45–3.85). Mother and father’s history of T2D (HR=1.73; 95% CI=1.46–2.05; HR=1.83; 95% CI=1.40–2.37) were associated with the risk of early-onset. Moreover, exercise (HR=1.23, CI=1.08–1.40) smoking status (HR=1.62, CI=1.32–1.99), and drinking (HR=1.32, CI=1.13–1.54) were associated with a higher risk for the early-onset. [Conclusion] Family history as well as life style including exercise, smoking, and drinking are the risk factors for early-onset factor in Korean population with T2D.</p>

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