Blood glucose is unlikely to be a prognostic biomarker in acute colitis with systemic inflammatory response syndrome in Thoroughbred racehorses

  • URAYAMA Shuntaro
    Racehorse Hospital, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan
  • ARIMA Daisuke
    Racehorse Hospital, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan
  • MIZOBE Fumiaki
    Racehorse Hospital, Ritto Training Center, Japan Racing Association, Shiga 520-3085, Japan
  • SHINZAKI Yuta
    Racehorse Hospital, Ritto Training Center, Japan Racing Association, Shiga 520-3085, Japan
  • NOMURA Motoi
    Racehorse Hospital, Ritto Training Center, Japan Racing Association, Shiga 520-3085, Japan
  • MINAMIJIMA Yohei
    Laboratory of Racing Chemistry, Tochigi 320-0851, Japan
  • KUSANO Kanichi
    Racehorse Hospital, Miho Training Center, Japan Racing Association, Ibaraki 300-0493, Japan

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<p>Although hyperglycemia at admission with colic has been reported to have a poor prognosis, there is no report specifically about acute colitis with systemic inflammatory response syndrome (SIRS) in horses. In this study, we measured blood glucose (Glu), insulin (Ins), and cortisol (Cor) levels in 17 Thoroughbred racehorses diagnosed as having acute colitis with SIRS, and examined the relationship between time-dependent changes in Glu, Ins, and Cor and prognosis. Glu levels were high in 3 horses at admission, but thereafter no horses had persistently high Glu levels. There was no significant difference in Glu, Ins, and Cor levels within 72 hr between surviving and non-surviving horses. In conclusion, the Glu level is unlikely to be a useful prognostic biomarker in acute colitis with SIRS.</p>

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