Miliary Tuberculosis in a Young Woman with Hemophagocytic Syndrome: A Case Report and Literature Review
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- Asaji Mina
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Tobino Kazunori
- Department of Respiratory Medicine, Iizuka Hospital, Japan Department of Respiratory Medicine, Juntendo University, School of Medicine, Japan
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- Murakami Koujin
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Goto Yuki
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Sueyasu Takuto
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Nishizawa Saori
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Yoshimine Kohei
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Munechika Miyuki
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Ko Yuki
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Yoshimatsu Yuki
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Tsuruno Kosuke
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Ide Hiromi
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Miyajima Hiroyuki
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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- Ebi Noriyuki
- Department of Respiratory Medicine, Iizuka Hospital, Japan
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抄録
<p>We herein report a rare case of miliary tuberculosis-associated hemophagocytic syndrome (HPS) complicated with respiratory failure. A 19-year-old Japanese woman with a fever, general malaise, and chest radiograph abnormalities was referred to our hospital. After admission, she developed respiratory failure with pancytopenia. A histological examination of lung and bone marrow biopsy samples revealed noncaseating granulomas without evidence of acid-fast bacilli or lymphoma. In addition, a bone marrow biopsy showed marked histiocyte hyperplasia with hemophagocytosis, and a bronchoalveolar lavage fluid culture grew Mycobacterium tuberculosis. Therefore, a diagnosis of miliary tuberculosis-associated HPS was made. The patient was successfully treated with antituberculous therapy. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 56 (12), 1591-1596, 2017
一般社団法人 日本内科学会