Successful Management of Pregnancy in a Patient with Systemic Lupus Erythematosus-associated Pulmonary Arterial Hypertension
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- Kawabe Akio
- The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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- Nakano Kazuhisa
- The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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- Aiko Yukiyo
- The Department of Obstetrics and Gynecology, School of Medicine, University of Occupational and Environmental Health, Japan
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- Aramaki Satoshi
- The Department of Obstetrics and Gynecology, School of Medicine, University of Occupational and Environmental Health, Japan
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- Onoue Takeshi
- The Second Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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- Okura Dan
- The Department of Anesthesiology, School of Medicine, University of Occupational and Environmental Health, Japan
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- Tanaka Yoshiya
- The First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan
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抄録
<p>Pregnancy in women with systemic lupus erythematosus (SLE)-associated pulmonary arterial hypertension (PAH) remains a high risk. We successfully managed a pregnancy in a patient with SLE-PAH. A 31-year-old pregnant woman with SLE-PAH had worsening PAH and SLE flare-up during pregnancy and a sudden increase in pulmonary arterial pressure after delivery. SLE-PAH was controlled by continuous intravenous epoprostenol and inhaled nitric oxide therapy combined with high-dose corticosteroids under close hemodynamic monitoring. Women with SLE-PAH should avoid pregnancy. However, in case of a similar event, we recommend our case as a good reference for improving the outcome of pregnancy with SLE-PAH. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 57 (11), 1655-1659, 2018-06-01
一般社団法人 日本内科学会