Do antilipidemic agents reduce blood pressure?

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  • Oyama Jun-ichi
    Department of Circulation Regulation in Medicine, Saga University
  • Uchida Fumi
    Department of Circulation Regulation in Medicine, Saga University
  • Node Koichi
    Department of Cardiovascular Medicine, Saga University

Abstract

<p>Currently, the prevalence of hypertension (HT), diabetes mellitus (DM), and hyperlipidemia (HL) is high, and these diseases are important risk factors for cardiovascular disease (CVD). Furthermore, patients with CVD often have more than one of these diseases. Generally, patients take multiple drugs for each disease. Therefore, clinicians must pay attention to drug interactions. Although HT, DM, and HL are different diseases, they share some of the same pathophysiological mechanisms and ultimately lead to the same cardiovascular events.</p><p>Currently, most patients with CVD are treated with 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors (statins), and various beneficial pleiotropic effects of statins have been reported since the 1990s.</p><p>In this review, we evaluate the additional effects of antihyperlipidemic agents on blood pressure (BP).</p>

Journal

  • Vascular Failure

    Vascular Failure 2 (1), 6-10, 2018-03-31

    Japan Society for Vascular Failure

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