Lung Sound Analysis and the Respiratory Cycle Dependence of Impulse Oscillometry in Asthma Patients
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- Shimoda Terufumi
- Clinical Research Center, Fukuoka National Hospital, Japan
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- Obase Yasushi
- Department of Respiratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Japan
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- Nagasaka Yukio
- Kyoto Respiratory Center, Otowa Hospital, Japan
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- Kishikawa Reiko
- Clinical Research Center, Fukuoka National Hospital, Japan
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- Iwanaga Tomoaki
- Clinical Research Center, Fukuoka National Hospital, Japan
抄録
<p>Objective A lung sound analysis (LSA) is useful for detecting airway inflammation and obstruction in patients with asthma. To elucidate the mechanism of LSA, we investigated the relationship between the exhalation-to-inhalation sound pressure ratio in the low frequency range between 100 and 195 Hz (E/I LF) and the respiratory cycle dependence of impulse oscillometry (IOS) parameters. </p><p>Methods Asthma patients underwent IOS [resistance of the respiratory system at 5 Hz (R5) and 20 Hz (R20), the reactance area (AX), resonant frequency of reactance (Fres), and reactance of the respiratory system at 5 Hz (X5) ], spirography, and an LSA. The correlation between the LSA-derived E/I LF values and the respiratory cycle dependence of the IOS parameters was analyzed. </p><p>Patients Thirty-four patients with mild to moderate bronchial asthma, who had not received oral or inhaled corticosteroids and who had no episodes of rumbling or wheezing were examined. </p><p>Results The E/I LF value was significantly correlated with the differences of the R5 and R5-R20 values between exhalation and inhalation (p=0.035 and p=0.050) in a multivariate analysis. </p><p>Conclusion E/I LF appears to be an index that expresses the respiratory cycle dependence of asthma as well as IOS. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 58 (1), 47-52, 2019-01-01
一般社団法人 日本内科学会