書誌事項
- タイトル別名
-
- Synthetic Aryne Chemistry toward Multicomponent Coupling
- タセイブン シュウセキ オ シコウ シタ ゴウセイ ノ タメ ノ アライン カガク
この論文をさがす
抄録
<p>Arynes with a highly reactive carbon-carbon triple bond are multipotent intermediates useful for preparing various multisubstituted arenes. To further enhance the synthetic utility of arynes, we have developed a wide range of synthetic methods involving aryne intermediates, including novel methods for aryne generation from o-sulfinylaryl triflates and o-iodoaryl triflates using phenyl or silylmethyl Grignard reagent, respectively. These methods allowed for the generation of new types of aryne intermediates that enabled facile syntheses of a wide variety of multisubstituted arenes such as aryl triflates, anilines, and benzoheterols. We also developed several novel transformations involving C-S or C-P bond formation via aryne intermediates, such as thioamination using sulfilimines, and several methods for preparing various o-silylaryl triflate-type aryne precursors that were difficult to be achieved by the conventional methods. These methods were demonstrated useful for preparation of a diverse range of multitriazoles and multisubstituted o-(arylthio)anilines by modular syntheses.</p>
収録刊行物
-
- 有機合成化学協会誌
-
有機合成化学協会誌 77 (2), 145-162, 2019-02-01
公益社団法人 有機合成化学協会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390001288122178816
-
- NII論文ID
- 130007595435
-
- NII書誌ID
- AN0024521X
-
- ISSN
- 18836526
- 00379980
-
- NDL書誌ID
- 029510744
-
- 本文言語コード
- ja
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可