Sick Sinus Syndrome Observed in a Patient with Cholinesterase Deficiency
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- Yasuda Shioto
- Heart Center, Kyushu University Hospital, Japan
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- Fukata Mitsuhiro
- Heart Center, Kyushu University Hospital, Japan
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- Yokoyama Taku
- Heart Center, Kyushu University Hospital, Japan
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- Arita Takeshi
- Heart Center, Kyushu University Hospital, Japan
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- Odashiro Keita
- Heart Center, Kyushu University Hospital, Japan Department of Medicine, Koga Central Hospital, Japan
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- Maruyama Toru
- Heart Center, Kyushu University Hospital, Japan Department of Medicine, Koga Central Hospital, Japan
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- Hiramoto Yoichiro
- Department of Medicine, Koga Central Hospital, Japan
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- Akashi Koichi
- Heart Center, Kyushu University Hospital, Japan
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抄録
<p>A 58-year-old woman complained of general fatigue and was diagnosed with sick sinus syndrome (SSS) by ambulatory electrocardiogram, which demonstrated sinus arrest at midnight and paroxysmal atrial fibrillation (AF) at nighttime. Since her plasma cholinesterase (ChE) activity had been persistently zero, she was diagnosed with ChE deficiency. She refused permanent pacemaker implantation, and treatment with positive chronotropic drugs is ongoing. A novel association of ChE deficiency with SSS is theoretically possible rather than coincident, considering that ChE plays a key role in cholinergic influences on the sinus node leading to sinus bradyarrhythmia and on the atria, causing vagally mediated AF. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 58 (6), 809-812, 2019-03-15
一般社団法人 日本内科学会