The Effect of Maternal Age at the First Childbirth on Gestational Age and Birth Weight: The Japan Environment and Children’s Study (JECS)
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- Kyozuka Hyo
- Fukushima Regional Center for the Japan Environmental and Children’s Study Department of Obstetrics and Gynecology, School of Medicine, Fukushima Medical University
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- Fujimori Keiya
- Fukushima Regional Center for the Japan Environmental and Children’s Study Department of Obstetrics and Gynecology, School of Medicine, Fukushima Medical University
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- Hosoya Mitsuaki
- Fukushima Regional Center for the Japan Environmental and Children’s Study Department of Pediatrics, School of Medicine, Fukushima Medical University
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- Yasumura Seiji
- Fukushima Regional Center for the Japan Environmental and Children’s Study Department of Public Health, School of Medicine, Fukushima Medical University
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- Yokoyama Tadahiko
- Fukushima Regional Center for the Japan Environmental and Children’s Study
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- Sato Akiko
- Fukushima Regional Center for the Japan Environmental and Children’s Study
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- Hashimoto Koichi
- Fukushima Regional Center for the Japan Environmental and Children’s Study Department of Pediatrics, School of Medicine, Fukushima Medical University
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抄録
<p>Background: In Japan, mean maternal age at first childbirth is increasing. The aim of this study was to investigate whether maternal age at the first childbirth is a risk factor for preterm birth (PTB), low birth weight (LBW), and small for gestational age (SGA).</p><p>Methods: We used the results of Japan Environment and Children’s Study (JECS) who gave birth in 2011–2014. Cases of primiparous singleton pregnancies where the subject was ≥20 years and delivered after 22 weeks were included. All subjects were categorized into five groups according to maternal age: 20–24, 25–29, 30–34, 35–39, and ≥40 years. Adjusted odds ratios (aORs) for PTB (before 37 and 34 weeks), LBW (<2,500 g and <1,500 g), and SGA were calculated using a logistic regression model, with the 20–24-year age group as reference.</p><p>Results: We analyzed 38,412 singleton primiparous pregnancies. The aORs of all outcomes increased in parallel with each maternal age group >30 years. The aORs of PTB before 37 and 34 weeks, LBW <2,500 g, LBW <1,500 g, and SGA in the 30–34-year age group were 1.39 (95% confidence interval [CI], 1.16–1.67), 2.23 (95% CI, 1.45–3.41), 1.34 (95% CI, 1.18–1.53), 2.30 (95% CI, 1.35–3.94), and 1.24 (95% CI, 1.05–1.46), respectively.</p><p>Conclusion: The present study showed that higher maternal age (>30 years) at the first childbirth was an independent risk factor for PTB, LBW, and SGA.</p>
収録刊行物
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- Ｊｏｕｒｎａｌ ｏｆ Ｅｐｉｄｅｍｉｏｌｏｇｙ
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Ｊｏｕｒｎａｌ ｏｆ Ｅｐｉｄｅｍｉｏｌｏｇｙ 29 (5), 187-191, 2019-05-05
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