Impact of Myocardial Fibrosis on Left Ventricular Function Evaluated by Feature-Tracking Myocardial Strain Cardiac Magnetic Resonance in Competitive Male Triathletes With Normal Ejection Fraction

DOI Web Site Web Site PubMed 参考文献21件
  • Tahir Enver
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg Eppendorf
  • Starekova Jitka
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg Eppendorf
  • Muellerleile Kai
    Department of General and Interventional Cardiology, University Heart Center
  • Freiwald Eric
    Institute for Medical Biometry and Epidemiology, University Hospital Hamburg Eppendorf
  • von Stritzky Alexandra
    Department of General and Interventional Cardiology, University Heart Center
  • Münch Julia
    Department of General and Interventional Cardiology, University Heart Center
  • Avanesov Maxim
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg Eppendorf
  • Weinrich Julius Matthias
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg Eppendorf
  • Stehning Christian
    Philips Clinical Science
  • Cavus Ersin
    Department of General and Interventional Cardiology, University Heart Center
  • Bohnen Sebastian
    Department of General and Interventional Cardiology, University Heart Center
  • Radunski Ulf K.
    Department of General and Interventional Cardiology, University Heart Center
  • Blankenberg Stefan
    Department of General and Interventional Cardiology, University Heart Center
  • Adam Gerhard
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg Eppendorf
  • Simon Perikles
    Department of Sports Medicine, Johannes Gutenberg University Mainz
  • Pressler Axel
    Department of Prevention, Rehabilitation and Sports Medicine, Klinikum rechts der Isar, Technische Universität München Center of Sports and Preventive Cardiology
  • Patten Monica
    Department of General and Interventional Cardiology, University Heart Center
  • Lund Gunnar K.
    Department of Diagnostic and Interventional Radiology and Nuclear Medicine, University Hospital Hamburg Eppendorf

この論文をさがす

抄録

<p>Background:To analyze the effect of myocardial fibrosis on left ventricular (LV) function evaluated by feature-tracking strain analysis by cine cardiac magnetic resonance (CMR) in competitive male triathletes with normal ejection fraction (EF).</p><p>Methods and Results:78 asymptomatic male triathletes with >10 weekly training hours (43±11 years) and 28 male age-matched controls were studied by late gadolinium enhancement (LGE) and cine CMR. Global and segmental radial, longitudinal and circumferential strains were analyzed using feature-tracking cine CMR. Focal non-ischemic LGE was observed in 15 of 78 triathletes (19%, LGE+) with predominance in the basal inferolateral segments. LVEF was normal in LGE+ (62±6%) and LGE− triathletes (62±5%, P=0.958). In contrast, global radial strain was lower in LGE+ triathletes at 40±7% compared with LGE− triathletes (45±7%, P<0.05). Reduced segmental radial strain occurred either in LGE+ segments or in directly adjacent segments. Strain analysis revealed regional differences in controls, with the highest radial and longitudinal strain in the inferolateral segments, which were typically affected by fibrosis in LGE+ triathletes.</p><p>Conclusions:Reduced global and regional radial strain suggests a negative effect of myocardial fibrosis on LV function in LGE+ triathletes with normal EF. The observed regional differences in controls with the highest radial and longitudinal strain in the inferolateral segments may explain the typical occurrence of fibrosis in this myocardial region in triathletes.</p>

収録刊行物

  • Circulation Journal

    Circulation Journal 83 (7), 1553-1562, 2019-06-25

    一般社団法人 日本循環器学会

参考文献 (21)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ