Suspected anaphylactic shock associated with administration of tranexamic acid in a dog
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- CHOI Jin-Young
- >Department of Veterinary Emergency Medicine, Konkuk Veterinary Medical Teaching Hospital, Konkuk University, 120, Neungdong-ro, Gwangjin-gu, Seoul, Republic of Korea, 05029 Department of Veterinary Surgery, Konkuk Veterinary Medical Teaching Hospital, Konkuk University, 120, Neungdong-ro, Gwangjin-gu, Seoul, Republic of Korea, 05029
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- KIM Jung-Hyun
- Department of Veterinary Internal Medicine, Konkuk Veterinary Medical Teaching Hospital, Konkuk University, 120, Neungdong-ro, Gwangjin-gu, Seoul, Republic of Korea, 05029
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- HAN Hyun-Jung
- >Department of Veterinary Emergency Medicine, Konkuk Veterinary Medical Teaching Hospital, Konkuk University, 120, Neungdong-ro, Gwangjin-gu, Seoul, Republic of Korea, 05029
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<p>A 10-year-old male castrated Maltese was referred with clinical signs of hematuria, stranguria, and pollakiuria. The dog was diagnosed with sterile hemorrhagic cystitis with urethroliths and cystoliths. To remove the uroliths, the dog underwent retrograde urohydropropulsion followed by a cystotomy. The following day, persistent bleeding in the urinary bladder was identified with large hematoma, hematuria and anemia. In order to reduce bleeding, the dog received 10 mg/kg of tranexamic acid (TXA) intravenously. Immediately after TXA administration, the dog developed anaphylactic shock manifested by hypotension, hypothermia, tachycardia and a dull mentation. Thus, an emergency treatment including bolus injection of crystalloid, administration of dexamethasone and diphenhydramine, and oxygen supplementation was given, after which the dog quickly recovered within a few minutes.</p>
収録刊行物
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- Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ
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Ｔｈｅ Ｊｏｕｒｎａｌ ｏｆ Ｖｅｔｅｒｉｎａｒｙ Ｍｅｄｉｃａｌ Ｓｃｉｅｎｃｅ 81 (10), 1522-1526, 2019
公益社団法人 日本獣医学会