A Novel Method for Reconstructing CT Images in GATE/GEANT4 with Application in Medical Imaging: A Complexity Analysis Approach

  • Gholami Neda
    Pattern Research Center
  • Dehshibi Mohammad Mahdi
    Department of Computer Science, Multimedia and Telecommunication, Universitat Oberta de Catalunya
  • Adamatzky Andrew
    Unconventional Computing Laboratory, University of the West of England
  • Rueda-Toicen Antonio
    Algorithmic Nature Group, LABORES for the Natural and Digital Sciences
  • Zenil Hector
    Algorithmic Nature Group, LABORES for the Natural and Digital Sciences Algorithmic Dynamics Lab, Unit of Computational Medicine, SciLifeLab, Centre for Molecular Medicine, Department of Medicine Solna, Karolinska Institute Oxford Immune Algorithmics, Oxford University Innovation
  • Fazlali Mahmood
    Department of Computer Science, Shahid Beheshti University
  • Masip David
    Department of Computer Science, Multimedia and Telecommunication, Universitat Oberta de Catalunya

抄録

<p>For reconstructing CT images in the clinical setting, ‘effective energy’ is usually used instead of the total X-ray spectrum. This approximation causes an accuracy decline. We proposed to quantize the total X-ray spectrum into irregular intervals to preserve accuracy. A phantom consisting of the skull, rib bone, and lung tissues was irradiated with CT configuration in GATE/GEANT4. We applied inverse Radon transform to the obtained Sinogram to construct a Pixel-based Attenuation Matrix (PAM). PAM was then used to weight the calculated Hounsfield unit scale (HU) of each interval's representative energy. Finally, we multiplied the associated normalized photon flux of each interval to the calculated HUs. The performance of the proposed method was evaluated in the course of Complexity and Visual analysis. Entropy measurements, Kolmogorov complexity, and morphological richness were calculated to evaluate the complexity. Quantitative visual criteria (i.e., PSNR, FSIM, SSIM, and MSE) were reported to show the effectiveness of the fuzzy C-means approach in the segmenting task.</p>

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