Thoracic myelopathy caused by calcification of the ligamentum flavum

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  • Miura Kousei
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan Department of Rehabilitation Medicine, Faculty of Medicine, University of Tsukuba, Japan
  • Koda Masao
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Abe Tetsuya
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Funayama Toru
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Noguchi Hiroshi
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Kumagai Hiroshi
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Nagashima Katsuya
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Mataki Kentaro
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Shibao Yosuke
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan
  • Yamazaki Masashi
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Japan

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<p>Calcification of the ligamentum flavum (CLF), which is a rare disorder that can potentially cause myelopathy, occurs uncommonly in the thoracic spine. Here, we report a rare case of thoracic myelopathy caused by CLF in a 78-year-old man. Magnetic resonance imaging (MRI) showed posterior spinal cord compression by a hypo-signal intense mass, and computed tomography (CT) revealed CLF and vacuum disc phenomenon at T10/11. After undergoing posterior decompression and instrumented fusion (T9–T12), the patient’s gait difficulties improved. The pathogenesis of CLF is largely unknown; however, it involves accumulation of calcium pyrophosphate dehydrate crystals (CPPD), and CLF from CPPD deposition tends to occur within a thickened and hypertrophic ligament. CLF occurs predominantly in the cervical spine and less frequently in the lumbar spine, with few cases involving the thoraco-lumbar spine. The thoracic spine is characterized by hypomobility; however, the thoraco-lumbar spine has a mobile segment which may potentiate CLF formation. Decompression with fusion surgery can be useful for treating patients with thoraco-lumbar CLF.</p>

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