Exercise Habits Are Associated with Improved Long-Term Mortality Risks in the Nationwide General Japanese Population: A 20-Year Follow-Up of the NIPPON DATA90 Study
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- Takatsuji Yuko
- Department of Hygiene and Public Health, Teikyo University School of Medicine
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- Ishiguro Aya
- Department of Hygiene and Public Health, Teikyo University School of Medicine
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- Asayama Kei
- Department of Hygiene and Public Health, Teikyo University School of Medicine
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- Ohkubo Takayoshi
- Department of Hygiene and Public Health, Teikyo University School of Medicine
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- Miura Katsuyuki
- Department of Public Health, Shiga University of Medical Science Center for Epidemiologic Research in Asia, Shiga University of Medical Science
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- Kadota Aya
- Department of Public Health, Shiga University of Medical Science Center for Epidemiologic Research in Asia, Shiga University of Medical Science
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- Yanagita Masahiko
- Faculty of Health and Sports Science, Doshisha University
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- Fujiyoshi Akira
- Department of Hygiene, Wakayama Medical University
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- Arima Hisatomi
- Department of Preventive Medicine and Public Health, Fukuoka University
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- Miyagawa Naoko
- International Center for Nutrition and Information, National Institute of Biomedical Innovation, Health and Nutrition
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- Takashima Naoyuki
- Department of Public Health, Faculty of Medicine, Kindai University
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- Kita Yoshikuni
- Faculty of Nursing Science, Tsuruga Nursing University
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- Hayakawa Takehito
- The Kinugasa Research Organization, Research Center for Social Studies of Health and Community, Ritsumeikan University
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- Kikuya Masahiro
- Department of Hygiene and Public Health, Teikyo University School of Medicine
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- Nakamura Yasuyuki
- Department of Public Health, Shiga University of Medical Science Yamashina Racto Clinic and Medical Examination Center
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- Okayama Akira
- Research Institute of Strategy for Prevention
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- Okamura Tomonori
- Department of Preventive Medicine and Public Health, School of Medicine, Keio University
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- Ueshima Hirotsugu
- Department of Public Health, Shiga University of Medical Science Center for Epidemiologic Research in Asia, Shiga University of Medical Science
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抄録
<p>Exercise habits are known as a protective factor for a variety of diseases and thus recommended worldwide; however, few studies have examined long-term effects of exercise habits on mortality. We continuously monitored death status in a nationwide population sample of 7,709 eligible persons from the National Integrated Project for Prospective Observation of Noncommunicable Disease and its Trends in the Aged in 1990 (NIPPON DATA90), for which baseline data were obtained in 1990. To investigate the long-term impact of baseline exercise habits, we calculated the relative risk of non-exercisers (participants without regular voluntary exercise habits) in reference to exercisers (those with these habits) for all-cause or cause-specific mortality using a Cox proportional hazard model, in which the following confounding factors were appropriately adjusted: sex, age, body mass index, total energy intake, smoking, drinking, and history of cardiovascular disease. During a median 20 years of follow-up, 1,747 participants died, 99 of heart failure. The risk for all-cause mortality was 12% higher in non-exercisers than in exercisers (95% confidence interval, 1%-24%), which was also observed for mortality from heart failure, as 68% higher in non-exercisers than in exercises (95% confidence interval, 3%-173%). These associations were similarly observed when the participants were divided to subgroups by sex, age, and the light, moderate, or vigorous intensity of physical activity, without any significant heterogeneities (P > 0.1). The present study has revealed significant impact of exercise habits on long-term mortality risks, supporting worldwide recommendations for improvement of exercise habits. </p>
収録刊行物
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 252 (3), 253-262, 2020
東北ジャーナル刊行会