Esthesioneuroblastoma: The UCLA experience 1970–1990

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<jats:title>Abstract</jats:title><jats:p>A retrospective review was conducted of all esthesioneuroblastoma cases treated at UCLA Medical Center from 1970 through 1990. Patients were staged according to the staging systems of Kadish, <jats:italic>et al.</jats:italic><jats:sup>12</jats:sup> Biller, <jats:italic>et al.</jats:italic>,<jats:sup>5</jats:sup> and a new staging system proposed by the authors.</jats:p><jats:p>Of 26 patients treated, 74% were alive at 5 years and 60% were alive at 10 years. Combined treatment with surgery and radiation is advocated since a recurrence'free status was achieved in 92% of the patients, compared with 14% for surgery alone and 40% for radiation alone. A craniofacial resection was performed in 7 patients, all of whom have remained disease free.</jats:p><jats:p>Negative prognostic factors included: age over 50 years at presentation, female sex, tumor recurrence, and metastasis. The proposed new staging system predicted disease'free status better than the other staging systems.</jats:p>

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