Arylsulfonamidothiazoles as a New Class of Potential Antidiabetic Drugs. Discovery of Potent and Selective Inhibitors of the 11β-Hydroxysteroid Dehydrogenase Type 1

• Tjeerd Barf

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Jerk Vallgårda

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Rikard Emond

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Charlotta Häggström

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Guido Kurz

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Alf Nygren

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Vivienne Larwood

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Erifili Mosialou

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Kent Axelsson

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Rolf Olsson

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Lars Engblom

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Naimie Edling

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Yuko Rönquist-Nii

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Birgitta Öhman

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Peteris Alberts

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

• Lars Abrahmsén

  Departments of Medicinal Chemistry, Chemical Technologies, Structural Chemistry, Assay Development and Screening, Preclinical R&D, and Biology, Biovitrum, Box 6443, SE-751 37, Uppsala, Sweden, and Computational Chemistry, BioFocus, 130 Abbott Drive, Sittingbourne Research Centre, Sittingbourne, Kent ME9 8AZ, U.K.

収録刊行物

• Journal of Medicinal Chemistry

  Journal of Medicinal Chemistry 45 (18), 3813-3815, 2002-08-01

  American Chemical Society (ACS)

キーワード

• Drug Discovery
• Molecular Medicine

詳細情報

• CRID: 1364233269667986304
• NII論文ID: 30011366322
• DOI: 10.1021/jm025530f
• ISSN: 15204804
• ISSN: 00222623
• ISSN: http://id.crossref.org/issn/00222623
• Web Site: https://pubs.acs.org/doi/pdf/10.1021/jm025530f
• データソース種別:
  • Crossref
  • CiNii Articles